| abstract |
The present invention relates to vesicles derived from Faecalibacterium praezeii and uses thereof. The present inventors have experimentally confirmed in clinical samples of patients with gastric cancer, colorectal cancer, liver cancer, pancreatic cancer, bile duct cancer, ovarian cancer, bladder cancer, lymphoma, myocardial infarction, atrial fibrillation and Parkinson's disease The vesicles were significantly reduced compared to normal humans, and the secretion of inflammatory mediators caused by pathogenic vesicles (eg, vesicles derived from E. coli) was significantly inhibited when vesicles isolated from the strain were administered. It is expected that the vesicles derived from Faecalibacterium pratense according to the present invention can be effectively used for development for diagnosis of gastric cancer, colorectal cancer, liver cancer, pancreatic cancer, cholangiocarcinoma, ovarian cancer, bladder cancer, lymphoma, myocardial infarction, atrium Methods of fibrillation and/or Parkinson's disease and objects of compositions for preventing, alleviating or treating said diseases. |