Predicate |
Object |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-53 |
filingDate |
2020-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2021-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2021-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-111575334-B |
titleOfInvention |
Method for preparing (S) -2-chloro-1- (3, 4-difluorophenyl) ethanol |
abstract |
The invention provides a method for preparing (S) -2-chloro-1- (3, 4-difluorophenyl) ethanol, which comprises the following steps: immobilizing keto reductase KRED by using an immobilized carrier LX-1000ODS or LXES-J420 to obtain an immobilized enzyme; catalyzing 2-chloro-1- (3, 4-difluorophenyl) ethanone by using immobilized enzyme to perform reduction reaction to obtain a target compound. The method can efficiently and stably catalyze the substrate reaction to generate a product with high optical purity, and is suitable for industrial application. |
priorityDate |
2020-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |