http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111575260-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-182 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 |
| filingDate | 2020-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111575260-B |
| titleOfInvention | Application of SAM dependent methyltransferase DmtMT2-1 |
| abstract | In order to solve the technical blank that DMTs adopt enzyme reaction to carry out methylation modification in the prior art, the invention provides SAM dependent methyltransferase DmtMT2-1 (derived from streptomyces marinus) Streptomyces sp.nrrl F-5123) in the preparation of methylated pre-DMTs and DMTs. Meanwhile, also provides an amino acid sequence and a nucleotide sequence of the methyltransferase; and provides a cloning and expression method of the methyltransferase. The methyltransferase DmtMT2-1 has broad substrate spectrum, can respectively use a plurality of pre-DMTs/DMTs as substrates to obtain N4 methylated pre-DMTs/DMTs, and on one hand, clears key obstacles for enzymatic methylation modified DMTs; on the other hand, the method also provides a new path for the development of diketopiperazine compounds, and has important application value and social significance. |
| priorityDate | 2020-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 204.