http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111560344-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-1369 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0697 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0619 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0793 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 |
| filingDate | 2020-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111560344-B |
| titleOfInvention | Method for constructing brain-like tissue by using umbilical cord mesenchymal stem cells |
| abstract | The invention discloses a method for constructing a brain-like tissue by using umbilical cord mesenchymal stem cells, which comprises the following steps: 1) carrying out stem cell culture on the human umbilical cord mesenchymal stem cell line to obtain subculture cells; 2) carrying out nerve induced differentiation on the subculture cells to obtain differentiated neuron precursor cells which are embryoid body-like neurospheres; 3) carrying out induction culture on the embryoid body-like neurospheres to obtain neural rosette neural tube-like structure neurospheres; 4) neural rosette neural tube-like structure neurospheres are subjected to differentiation culture to obtain human-like brain organs which comprise various types of neuron mixtures. The invention differentiates the human mesenchymal stem cells into a plurality of neurons for the first time and constructs the brain-like tissue which can be used as a drug screening platform and has wide application prospect. |
| priorityDate | 2020-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 205.