abstract |
The present disclosure relates to closed system cryogenic vessels for needle-free pipetting of biomedical materials. The needle-free removal may reduce damage to the biomedical material inside the vessel, allow for greater recovery of biomedical material from the vessel, and reduce the amount of effort required to remove the biomedical material from the vessel. exposure risks for users of closed-system cryogenic vessels. In some aspects, the vessel can be used to store or package a composition of cells, such as a composition containing engineered cells, including engineered cells in combination with adoptive cell therapy. Articles of manufacture, kits and methods are also provided. |