http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111548411-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-085 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-42 |
| filingDate | 2020-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111548411-B |
| titleOfInvention | Monoclonal antibody for neutralizing EB virus and application thereof |
| abstract | The invention discloses an antibody of EB virus for the first time, which consists of a light chain and a heavy chain, wherein the heavy chain variable region of the heavy chain is provided with 3 complementary regions CDR1, CDR2 and CDR3, the amino acid sequences of the complementary regions are respectively shown as SEQ ID No. 1-3, and the light chain variable region of the light chain is provided with 3 complementary regions CDR1 ', CDR2 ' and CDR3 ', the amino acid sequences of the complementary regions are respectively shown as SEQ ID No.4, GAS and SEQ ID No. 5. The antibody can block EBV from infecting epithelial cells, IC50 is 53ng/ml, and the antibody has no neutralization effect on Ebola virus infection, which indicates that the antibody has high capability of specifically neutralizing EBV infected epithelial cells. |
| priorityDate | 2020-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 573.