http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111544430-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 |
| filingDate | 2020-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111544430-B |
| titleOfInvention | Application of melatonin in preparation of medicine for inhibiting and/or killing bacteria |
| abstract | The invention provides an application of melatonin in preparation of a medicine for inhibiting and/or killing bacteria, and relates to the technical field of medicines. The research of the invention discovers that the small molecular substance melatonin (melatonin) has obvious bacteriostatic or bactericidal action, and the melatonin destroys the metabolic flux of bacteria by specifically targeting citrate synthase in gram-negative bacteria, so that in an in vivo infection model of Pasteurella multocida, the melatonin effectively reduces the bacterial colonization in the lung and improves the survival rate of mice, thereby providing effective guarantee for the prevention and/or treatment of pathogenic bacteria infection diseases and providing theoretical basis for the development of harmless, pollution-free, safe and effective new drugs. |
| priorityDate | 2020-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 344.