| abstract |
Compositions and methods for pyrithione compounds and pharmacologically acceptable salts thereof are described. The present invention provides topical methods of administration for treating skin cancer, treating cervical cancer, treating other cancers, preventing the development of skin cancer from premalignant lesions, preventing the development of cervical cancer from chronic Human Papillomavirus (HPV) infection, preventing the development of other cancers from chronic HPV infection. Also disclosed are compositions comprising at least one pyrithione compound, ethylenediaminetetraacetic acid (EDTA), ascorbic acid, any salt thereof and chemical derivatives thereof, pyridoxine and any derivatives thereof, and a pharmacologically acceptable buffer. The pH in these compositions was adjusted to 4.5 to 6.4. |