http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111529494-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-146 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-575 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 |
| filingDate | 2020-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111529494-B |
| titleOfInvention | Oryzanol micelle compound solid dispersion and preparation method thereof |
| abstract | The invention belongs to the technical field of pharmaceutical preparations, and discloses a oryzanol micelle compound solid dispersion and a preparation method thereof. The oryzanol micelle compound solid dispersion is composed of oryzanol, an amphiphilic block copolymer and a water-soluble carrier material, the oryzanol micelle compound is prepared by controlling the mass ratio of the oryzanol to the amphiphilic block copolymer, such as PEG-PCL, and the oryzanol micelle compound is further prepared into the solid dispersion by taking the water-soluble carrier material, such as PVP K30, as a carrier. The preparation not only improves the in vitro dissolution and solubility of the oryzanol, but also obviously improves the bioavailability of the oryzanol. The oryzanol polymer micelle can also stabilize the amorphous structure of the oryzanol in the solid dispersion, and avoid the aging of the solid dispersion. |
| priorityDate | 2020-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.