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filingDate 2018-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2020-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111526896-A
titleOfInvention Method for preparing an osteoconductive polymer article and osteoconductive polymer article prepared therefrom
abstract The present disclosure relates to a method of making an osteoconductive polymer article for use as an orthopaedic implant, comprising the steps of: forming an article from a biocompatible, non-biodegradable polymer, the article comprising a roughness Ra of at least 5 μm a non-planar surface; providing a dispersion of bioactive ceramic particles having a particle size of up to 10 μm in a first solvent, the first solvent comprising a solvent for a polymer; coating at least the non-flat surface with the dispersion in at least one step a flat surface; and rinsing the coated article with a second solvent, which is a non-solvent for the polymer, to substantially remove the first solvent. Also disclosed is an osteoconductive polymer article for use as an orthopaedic implant, the article being made of a biocompatible, non-biodegradable polymer and comprising a non-planar surface having a roughness Ra of at least 5 μm, wherein the particle size Bioactive ceramic particles up to 10 μm are partially embedded in the polymer at the surface of the article. This approach exhibits the advantage of being easy to modify the surface layer with bioactive particles, applying mild conditions and requiring no additional additives or post-treatments, or not significantly affecting bulk polymer properties, and yielding properties that adhere to the surface while still being able to Orthopedic implant articles of particles that interact with surrounding tissue or fluids.
priorityDate 2017-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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