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filingDate 2020-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111518157-B
titleOfInvention A kind of triptolide derivative and its preparation method and application
abstract The present invention provides a triptolide derivative, which has the structure shown in formula I: where n is an integer of 4-10. The triptolide derivatives of the present invention have better selectivity to tumor cells while retaining better anti-tumor activity, reduce toxicity to normal cells, and have better water-solubility, which is beneficial to the efficacy of drugs. Absorbing and exerting drug effect in vivo, reducing adverse reactions, the triptolide derivative of the present invention has the potential as an antitumor drug.
priorityDate 2020-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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