| abstract |
The invention discloses a γ-alkenyl ketone and a preparation method thereof. Simple cyclic ketones such as cyclopentanone or acyclic methyl ketones, and 1-phenyl-1-propyne are used as raw materials, and are prepared in an organic solvent and a catalyst. In the presence of , additives and ligands, the target product can be obtained with high yield, high regioselectivity and high enantioselectivity. The invention has the advantages of atom economy, high regioselectivity, high enantioselectivity and the like, and can realize the efficient conversion of cheap basic organic chemicals to high value-added γ-alkenyl ketones. The γ-alkenyl ketone synthesized by the invention is a potential synthetic intermediate and has potential application prospects in the synthesis of fine chemicals and the synthesis of pharmaceutical intermediates. |