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filingDate 2020-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111514107-B
titleOfInvention Active oxygen response type vesicle and preparation method thereof
abstract The invention discloses an active oxygen response type vesicle and a preparation method thereof. According to the invention, the quaternary ammonium salt surfactant with the hydrophilic head group containing aldehyde group and the selenylamine are mixed at room temperature to generate the active oxygen response type surfactant containing dynamic imine bonds in situ, and when the concentration is more than 0.05mmol/L, the system can be self-assembled to form vesicles. Under the existence of active oxygen with lower concentration, the vesicle can be disintegrated in a short time, so that the loaded medicine can be released, and the vesicle can be used for the site-specific targeted rapid release of inflammatory medicines.
priorityDate 2020-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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