http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111505141-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-065 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-8679 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-8665 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
| filingDate | 2020-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111505141-B |
| titleOfInvention | High-throughput screening method for non-target biomarkers based on pollutant metabolic disturbance |
| abstract | The invention discloses a high-throughput screening method for non-target biomarkers based on pollutant metabolism disturbance, belonging to the field of environmental exposure and health, and comprising the following steps of: (1) extracting to obtain an extracting solution to be detected; (2) performing chromatographic analysis to obtain a spectrogram containing chromatographic peaks; (3) identifying and labeling pollutant characteristic peaks, taking chromatographic peaks except the pollutant characteristic peaks as potential metabolite characteristic peaks, and performing non-target labeling on the potential metabolite characteristic peaks; (4) establishing a linear regression model by taking the peak area of the characteristic peak of the potential metabolite as a dependent variable and the peak area of the characteristic peak of the pollutant as an independent variable; (5) running the model, and carrying out non-target screening on the biomarkers to preliminarily obtain related biomarkers; (6) and identifying the primary and secondary spectrograms of the preliminarily obtained biomarkers to identify the biomarkers related to pollutant exposure. |
| priorityDate | 2020-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.