Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_618763934cfcbc50b4d31fb42059456b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-154 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6858 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6858 |
filingDate |
2020-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3a023d2b7a088024159cf77d93043e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8a3ef832693171ee477b1783fbc82ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af1bc56f14f70969b2393eca96d24ce9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_473387e3c417ea52b41b04a4eecc6f38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36cab6fd405682df24edc38a83d2a26f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed383389a2c6fe67c2fb9ff532676b2e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_faaf8c7cecd51770f06aff7d0451af0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9cdb8058ca7a29e71a0a80839728dfbf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf9abec2d11389cf076afac11fe93458 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2351d3613d5584eb41143ad8dd6ade5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39ca5eebe68727d338e13520beb7ab79 |
publicationDate |
2020-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-111500731-A |
titleOfInvention |
A kit for early diagnosis, detection or screening of thyroid cancer and its using method and application |
abstract |
The invention discloses a kit for early diagnosis, detection or screening of thyroid cancer, a method of use and application thereof. The kit includes specific primers and probes for detecting or measuring the methylation status or level of one or more specific genes in the DNA of the test sample, the specific genes being BNC1 and ACTB. The kit of the invention can significantly improve the positive detection rate and specificity (true negative rate) of early-stage thyroid cancer, and can improve the detection sensitivity of biomarkers to picogram/nanogram DNA molecules. The improvement of detection sensitivity is achieved by optimizing Specific nucleotide sequence primers and DNA probes and improved plasma-free DNA bisulfite treatment method to achieve. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113999907-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113699242-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114507734-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114507734-A |
priorityDate |
2020-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |