http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111500564-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y305-01011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P35-04 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-025 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 |
filingDate | 2020-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111500564-B |
titleOfInvention | Penicillin G acylase mutant and application thereof in enzymatic synthesis of cefamandole |
abstract | The invention relates to a penicillin G acylase mutant and application thereof in enzymatic synthesis of cefamandole. The PGA mutant with higher reaction activity, faster reaction rate and better conversion rate is obtained by mutating penicillin G acylase from xylose oxidizing Achromobacter (Achromobacter xylosoxidans) PX02 by a semi-rational enzyme engineering technology. The PGA mutant has greatly reduced hydrolysis activity to the product, hardly hydrolyzes the product after the yield reaches the maximum value, and has wide industrial application prospect. |
priorityDate | 2020-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 443.