http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111500517-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-625 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-225 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-53 |
filingDate | 2020-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111500517-B |
titleOfInvention | Recombinant strain for producing L-lactic acid, construction method thereof, method for producing L-lactic acid by fermentation and application thereof |
abstract | The invention relates to the field of genetic engineering and the field of microbial fermentation, and discloses a recombinant strain for producing L-lactic acid, a construction method thereof, a method for producing L-lactic acid by fermentation and application thereof, wherein the recombinant strain is obtained by genetically modifying an original strain, and compared with the original strain, the activity of D-lactic dehydrogenase of the recombinant strain is weakened or inactivated, and the activity of L-lactic dehydrogenase is enhanced; the construction method comprises the following steps of carrying out genetic modification on an original strain so as to weaken or inactivate the activity of D-lactate dehydrogenase of the original strain and enhance the activity of L-lactate dehydrogenase of the original strain; the method for producing L-lactic acid by fermentation comprises the steps of inoculating the recombinant strain to the method for constructing the recombinant strain, and inoculating the obtained recombinant strain to an acid-producing fermentation culture medium for fermentation; the method obviously improves the fermentation effect, the yield of the L-lactic acid and the optical purity of the product L-lactic acid. |
priorityDate | 2020-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 576.