http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111499888-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2343-02 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-243 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0024 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J3-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F230-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-32 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F230-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-243 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-06 |
| filingDate | 2020-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2023-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2023-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111499888-B |
| titleOfInvention | Preparation and application method of hypoxic degradable phosphorylcholine polymer nanogel |
| abstract | The preparation method of hypoxic degradable phosphorylcholine polymer nanogel, firstly utilizes amide reaction to prepare hypoxic degradable cross-linking agent containing azophenyl group, and secondly adopts the method of reflux precipitation polymerization to synthesize phosphorylcholine Zwitterionic monomers and azo-type hypoxic degradable initiators react in organic solvents to obtain hypoxic degradable phosphorylcholine polymer nanogels; the application method of hypoxic degradable phosphorylcholine polymer nanogels, The hypoxic-degradable phosphorylcholine polymer nanogel product is used as a carrier, and the nanogel is used to load antitumor drugs to treat tumors. The finished product prepared by the present invention is used in tumor treatment, can maintain high stability in the process of blood circulation and has the ability to hide, and is not easy to be recognized and swallowed by the endothelial reticular system, and the nanogel quickly reaches the hypoxic environment of the tumor. It can effectively degrade and release the loaded drug, thereby effectively killing tumor cells, providing a strong technical support for cancer treatment. The present invention has good prospects. |
| priorityDate | 2020-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.