| abstract |
The present invention discloses an immunomodulator, and specifically discloses a compound represented by formula I, or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof. The compound provided by the invention can effectively combine with STING, has good activating function of STING protein, and shows good inhibitory effect on various tumors. Therefore, the compounds of the present invention are useful as STING agonists and for the treatment of various related disorders. The compounds of the present invention are used in the preparation of medicaments for treating diseases related to STING activity (especially medicaments for treating inflammatory diseases, allergic diseases, autoimmune diseases, infectious diseases, cancer or precancerous syndromes) and in the preparation of immune adjuvants It has very good application prospects, and provides a new option for clinical screening and/or preparation of drugs for diseases related to STING activity. |