http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111499560-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_08fd3fe9f9e4e9852dd7325b6b009af4 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-32 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-32 |
| filingDate | 2020-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fd5ebdca8a54ec43e6f61b4dd539191 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f77aee7d4d6665a04c83cb76a0458ed7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1391f80e3fe343876ada42c02c3fa7f |
| publicationDate | 2020-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111499560-A |
| titleOfInvention | A kind of purification method of donepezil hydrochloride key intermediate compound |
| abstract | The invention discloses a method for purifying a key intermediate compound of donepezil hydrochloride. The crude product molecular formula of the compound (I) is: In the presence of alumina-supported potassium fluoride (KF·Al 2 O 3 ), in a C 6 -C 12 organic solvent containing benzene aromatic hydrocarbons, the reaction is stirred at 70 - 110 ° C for 0.5 - 3 h to obtain high Purity compound (I), wherein the organic solvent containing benzene aromatic hydrocarbons at C 6 to C 12 is selected from one of the following: benzene, toluene, xylene, the present invention is easy to operate, high in yield, good in product purity, and suitable for industrialization Production. |
| priorityDate | 2020-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.