http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111494650-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6933 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0093 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0054 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 |
| filingDate | 2020-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111494650-B |
| titleOfInvention | Preparation method and products of amphiphilic polymer nanoparticles based on near-infrared fluorescence imaging and reduction response |
| abstract | The invention discloses a preparation method and products of amphiphilic polymer nanoparticles based on near-infrared fluorescence imaging and reduction response. The preparation method includes: (1) preparation of reduction-responsive MABHD; (2) preparation of reduction-responsive MABHD-CPT; (3) Preparation of hydrophilic POEGMA; (4) Preparation of amphiphilic POEGMA-PMABHD; (5) Preparation of intermediate POEGMA-PMABHD-PNPCF; (6) Reduction-responsive amphiphilic polymer prodrug delivery Preparation of systematic PCC; (7) Preparation of PCC nanoparticles; polymer prodrugs are responsive to the highly reducing environment in tumor cells, and disulfide bonds in polymer prodrugs are opened to realize fluorescent dye CyOH and chemotherapeutic drug CPT It has the characteristics of high stability, controllable drug release, sensitive fluorescence imaging and good biocompatibility. |
| priorityDate | 2020-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.