http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111484469-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0057 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D309-34 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2020-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111484469-B |
| titleOfInvention | Synthesis method and application of lead compound of pyranidene malononitrile photosensitizer |
| abstract | Synthesis method of lead compound of pyrylanidene malononitrile type photosensitizer and application thereof Small molecule photosensitizer (PS1-3), the structure is shown in formula (I), and its photodynamic properties and fluorescence properties are different. The invention also discloses the application of tumor imaging and treatment at the cell level. The lead compound in the present invention has the characteristics of simple structure, small molecular weight, definite chemical structure, easy preparation, purification and further modification, and low cytotoxicity. Cell experiments have shown that near-infrared imaging and photodynamic therapy of cells can be achieved with the help of an external visible light source, which significantly inhibits tumor growth. Therefore, the single-molecule photosensitizer lead compound involved in the present invention has a good application prospect in breast cancer treatment. |
| priorityDate | 2020-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.