http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111481734-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-04 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-0015 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-04 |
| filingDate | 2020-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111481734-B |
| titleOfInvention | Modified sodium alginate self-developing embolism microsphere and preparation method and application thereof |
| abstract | The invention relates to the technical field of biological medicines, and particularly discloses a modified sodium alginate self-developing embolism microsphere as well as a preparation method and application thereof. The modified sodium alginate self-developing embolism microsphere comprises: modified sodium alginate and a developer; the modified sodium alginate is prepared by performing branching modification to introduce a plurality of hydroxyl groups, and then performing hydrophobic modification and sulfonation modification, wherein the branching substitution rate of the branching modification is 22-81%; the hydrophobic substitution rate of the hydrophobic modification is 5-32%; the sulfonation substitution rate of the sulfonation modification is 57-266%. When the embolism microsphere is used as a drug carrier, the drug loading rate and the drug loading rate of negatively charged drugs can be remarkably improved, the drug release time can be delayed, and the burst release of the drugs can be reduced. |
| priorityDate | 2020-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 88.