| abstract |
The invention discloses the application of IDHP for preparing medicine for treating and/or preventing sepsis and myocardial injury induced by it. The research of the present invention found that IDHP can inhibit the decline of survival rate caused by sepsis, and reduce the levels of WBC, LYM, MON, GRA and LDH; at the same time, IDHP can also inhibit the high expression of myeloperoxidase and Ly6C after myocardial tissue damage caused by sepsis And cardiomyocyte apoptosis, play anti-inflammatory, anti-apoptotic effects; and, it is also found that IDHP has the effect of improving cardiac systolic function. |