http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111471193-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2303-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2489-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2305-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J3-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J3-075 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L89-00 |
| filingDate | 2020-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111471193-B |
| titleOfInvention | Dialdehyde polysaccharide nanoparticle crosslinked collagen hydrogel and preparation method thereof |
| abstract | The invention discloses dialdehyde polysaccharide nanoparticle crosslinked collagen hydrogel and a preparation method thereof. Firstly, carrying out cholesterol group hydrophobic modification on polysaccharide, then specifically oxidizing the polysaccharide by utilizing sodium periodate to prepare an amphiphilic polysaccharide derivative with a dialdehyde structure, and then self-assembling the amphiphilic polysaccharide derivative in an aqueous solution to form dialdehyde polysaccharide nano-particles with a core-shell structure; then mixing and stirring 3-6% of dialdehyde polysaccharide nano-particle solution and 0.4-0.9% of collagen solution according to the volume ratio of 1 (0.5-1.5), and standing at 30-37 ℃ for 24h to prepare the dialdehyde polysaccharide nano-particle crosslinked collagen hydrogel. The invention has the advantages that: the green and harmless dialdehyde polysaccharide nano-particles are used as a cross-linking agent, and the prepared hydrogel has uniform aperture, good mechanical property and good biocompatibility, and has good application prospect in the field of tissue engineering scaffold materials. |
| priorityDate | 2020-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.