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filingDate 2020-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111471047-B
titleOfInvention Method for selectively synthesizing pyrazolo [1,2-a ] pyrazolone or 2-acyl indole compounds
abstract The invention discloses a method for selectively synthesizing pyrazolo [1,2-a ] pyrazolone or 2-acyl indole compounds, belonging to the technical field of organic chemistry. The method is characterized in that a pyrazolo [1,2-a ] pyrazolone 3 or 2-acyl indole compound 4 is synthesized with high selectivity by starting from a 1-aryl pyrazolone compound 1 and an alkynyl cyclobutanol compound 2 and changing the reaction temperature, the solvent and the types of additives under the catalysis of dichloro (pentamethylcyclopentadienyl) rhodium (III) dimer. The method has the advantages of simple and easily obtained raw materials, simple and convenient operation, mild conditions, good selectivity, wide substrate application range and the like.
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