http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111467580-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-041 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-16 |
| filingDate | 2020-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111467580-B |
| titleOfInvention | Temperature-sensitive composition for treating periodontal diseases and preparation method thereof |
| abstract | The present invention provides a temperature-sensitive composition for treating periodontal disease, comprising: an aqueous medium; sodium carboxymethylcellulose; a therapeutically effective amount of polylysine-modified hyaluronic acid or a pharmaceutically acceptable salt thereof; and temperature-sensitive material hydroxypropyl chitin, in the hydroxypropyl chitin, the substitution degree of hydroxypropyl to chitin is 1.0-1.5, and the amount of sodium carboxymethyl cellulose in the temperature-sensitive composition is enough to make the temperature-sensitive composition have the viscosity of 10 Pa.s-40 Pa.s at room temperature. The temperature-sensitive composition is in a viscous solution state before being applied to the inside of the oral cavity, can quickly form a gel state when being applied to the inside of the oral cavity, and can be well adhered to an application site, so that the action time of the hyaluronic acid modified by polylysine serving as an active ingredient in the gel on an affected part is prolonged, and the treatment effect is further improved; meanwhile, the hyaluronic acid modified by polylysine serving as an active ingredient in the temperature-sensitive composition has antibacterial property while the physiological activity of the hyaluronic acid is kept. |
| priorityDate | 2020-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.