http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111467510-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K101-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K103-34 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 |
| filingDate | 2020-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111467510-B |
| titleOfInvention | Specific targeting radionuclide marker and preparation method and application thereof |
| abstract | The invention provides a specific targeting radionuclide marker and a preparation method and application thereof, belonging to the technical field of nano medicine and molecular imaging. The tumor cell nucleus targeted fluorescent nanoprobe (GTTN) based on graphene is used as a cell nucleus targeted molecule to mark the radionuclide, and the obtained marker can be directly used for Single Photon Emission Computed Tomography (SPECT) and positron emission computed tomography (PET) of a tumor region and can be used for radionuclide treatment; in addition, the marker can highly target a tumor region by utilizing a cell membrane permeability targeting mechanism of GTTN, can realize bimodal imaging through fluorescence imaging of GTTN and SPECT or PET imaging of radionuclide, achieves the effects of accurate diagnosis and treatment, simultaneously reduces the side effect of the radionuclide on normal tissues to the maximum extent, and has good clinical application prospect. |
| priorityDate | 2020-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.