http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111467497-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2503-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y114-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5061 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-864 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate | 2020-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111467497-B |
| titleOfInvention | Application of FTO (fluorine-doped tin oxide) as target point in treatment of pressure-loaded myocardial injury |
| abstract | The present invention relates to the use of FTO (fat and obesity related) proteins as targets in the treatment of pressure-loaded myocardial injury. The invention proves that FTO down-regulation is an important reason for myocardial damage after the heart is stimulated by pressure overload; compared with a model group mouse, the myocardial glucose uptake of the pressure-loaded myocardial injury mouse with the over-expression FTO is obviously increased, and the cardiac function is obviously improved, so that the over-expression FTO can treat the myocardial injury after pressure overload, and the FTO is a medicine target for treating the pressure-loaded myocardial injury. The invention also provides an FTO overexpression vector with obvious curative effect. The invention has the advantages that: the application of FTO as a therapeutic target for improving the pressure-loaded myocardial damage is developed, and a new medicine research direction is provided for the pressure-loaded myocardial damage diseases; provides a medicament which has a clinical application prospect and takes FTO as a target spot for myocardial damage after pressure overload. |
| priorityDate | 2020-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 152.