http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111450252-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 |
| filingDate | 2020-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2023-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2023-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111450252-B |
| titleOfInvention | A kind of medicine for blocking tumor blood vessels and its preparation method and application |
| abstract | The invention discloses a medicine for blocking tumor blood vessels, a preparation method and application thereof. The drug for blocking tumor blood vessels includes biomembranes, MOFs, endogenous proteins, and targeting molecules; wherein, MOFs are wrapped in biomembranes; endogenous proteins are loaded on MOFs; targeting molecules are linked to biological outside of the membrane. The present invention also provides a preparation method of the drug, which is to synthesize MOFs loaded with endogenous proteins through a one-pot method, then add biofilm, stir, sonicate, extrude and coat; then add phospholipid-polyethylene glycol-targeted Molecules are mixed and incubated, and then freeze-dried to obtain drugs for targeting blocked tumor blood vessels. The drug can specifically identify and block tumor neovascularization, causing tumor cells to die due to lack of nutrition and oxygen starvation without affecting normal cells; it has unprecedented potential in the field of tumor treatment. |
| priorityDate | 2020-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 165.