http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111450242-A

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filingDate 2019-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e4ede36c7c43cf0b0dd456919fb2adc
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publicationDate 2020-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111450242-A
titleOfInvention Bivalirudin injection preparation and preparation method and application thereof
abstract The invention discloses a bivalirudin injection preparation and a preparation method and application thereof. The injection preparation comprises bivalirudin or pharmaceutically acceptable salt thereof, an osmotic pressure regulator, a pH regulator and a solvent, wherein the pH value of the bivalirudin injection preparation is 5.0-7.0; the bivalirudin injection preparation does not contain a stabilizer and a freeze-drying protective agent. The bivalirudin injection preparation is convenient to use clinically, high in safety and good in stability, and trehalose is not used as an auxiliary material, so that the medication safety of patients is improved; in the production process, long-time sublimation drying and desorption drying are not needed, the process time is shortened, the energy consumption is reduced, and the production efficiency is improved.
priorityDate 2019-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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