http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111440215-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J19-0093 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6561 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561 |
| filingDate | 2020-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111440215-B |
| titleOfInvention | Method for preparing Reidesvir by using microchannel reaction device |
| abstract | The invention discloses a method for preparing Rudexilvir by a microchannel reaction device, which comprises the following steps of (1) dissolving a compound shown as a formula I in an organic solvent to obtain a first reaction liquid; hydrochloric acid is used as a second reaction liquid; (2) and respectively and simultaneously pumping the first reaction liquid and the second reaction liquid into a micro mixer of the microchannel reaction device, mixing, introducing into a micro reactor for reaction, and collecting effluent liquid. Compared with the prior art, the microchannel reaction device has better reaction heat removal capacity and cooling capacity, strong acid can be added at room temperature, the microchannel reaction device has better mass and heat transfer efficiency, the safety coefficient of the reaction is improved, and meanwhile, the microchannel reaction device adopts a continuous flow mode, so that the material mixing effect is good, the back mixing is extremely low, the reaction selectivity can be effectively improved, and the product quality is improved. The conversion rate of the raw materials is 75-92%, and the yield of the product is up to 70-86%. |
| priorityDate | 2020-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.