http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111440183-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 |
| filingDate | 2019-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111440183-B |
| titleOfInvention | Compound, preparation method and application thereof, and anti-rheumatoid arthritis drug |
| abstract | The invention discloses a compound, a preparation method and application thereof, and a medicament for resisting rheumatoid arthritis, and relates to the technical field of natural medicaments and medicaments. The compound is new compound, and can be 9 kinds of extract glytacoumestan A-I in tobacco bean. The compound is extracted from the tobacco beans, and the compound is applied to the preparation of the rheumatoid arthritis drug, and pharmacodynamic tests show that the coumestan compound can remarkably relieve cell inflammation reaction stimulated by Lipopolysaccharide (LPS) and interleukin-1 beta (IL-1 beta), and can inhibit the differentiation of osteoclasts, thus prompting the application prospect of the compound in the preparation of the anti-rheumatoid arthritis drug. Therefore, the invention provides a candidate compound for researching and developing a new anti-rheumatoid arthritis medicament and provides a scientific basis for comprehensively developing and utilizing the tobacco bean resources. |
| priorityDate | 2019-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 106.