| abstract |
The present application discloses the use and preparation method of bovine serum albumin-based fucose glycomimetic protein (Fuc-BSA) in inhibiting Aggregatibacter segnis (A. segnis). Its inhibitory effect is reflected in reducing the adhesion of A. segnis to oral cells CAL-27 and HOEC, and reducing the cytotoxicity of A. segnis. Moreover, according to this, it can also be clarified that: the use of bovine serum albumin-based fucose glycomimetic protein (Fuc-BSA) in the preparation of health food/medicine for preventing diseases caused by A. segnis, the health food / The drug acts on the oral cavity (administered directly to the infection site), and the diseases caused by A. segnis can be endocarditis, appendicitis, cholecystitis, pancreatic abscess and the like. |