| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_81ba2c4156354c844d4a8883be561f00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-685 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4188
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-685
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N5-10 |
| filingDate |
2018-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2213078286cf91cf7089d66c1366af80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6a18738d3255a09ccfe482ff623e8f1 |
| publicationDate |
2020-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-111432816-A |
| titleOfInvention |
Combination therapy with fractionated radiation and SAPC-DOPS for the treatment of tumors |
| abstract |
A method of treating a malignant solid tumor in a patient in need thereof is provided, the method comprising administering to the patient a combination therapy comprising: fractionated radiation therapy and a therapeutically effective amount of saposin C (SapC) and dioleoyl Phosphatidylserine (SapC-DOPS), wherein fractionated radiation therapy comprises multiple radiation fractions, each delivering a radiation dose lower than the dose effective to inhibit tumor growth when administered alone. Also provided are methods of enhancing the anti-tumor efficacy of SapC-DOPS. |
| priorityDate |
2017-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |