http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111426833-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6432 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6439 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56966 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
| filingDate | 2020-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111426833-B |
| titleOfInvention | Preparation method of nano hybrid probe for visually detecting tumor exosomes |
| abstract | The invention discloses a preparation method of a nano hybrid probe for visually detecting tumor exosomes, wherein a novel dual-emission nano hybrid carrier probe is prepared on the basis of copper ion coordination black phosphorus quantum dots (Cu-BPQDs) and organic fluorescent dye (Cy5), and the probe can be used for visually semi-quantitatively detecting breast cancer exosomes. The sample containing the exosome is added into the aqueous dispersion of the probe, so that a DNA molecular valve on the surface of the probe is opened, the loaded electron acceptor molecules are released, the blue fluorescence of the Cu-BPQDs is converted from quenching to fluorescence recovery, and the process has little influence on the Cy5 red fluorescence. As the concentration of exosomes in the sample increases, the fluorescence color of the probe-sample mixed dispersion gradually changes from red to blue, including a variety of intermediate transition colors. And establishing the correlation between the exosome concentration in the sample and the fluorescence color type of the probe-sample mixed dispersion liquid, and developing a new method for visually detecting the tumor exosomes. |
| priorityDate | 2020-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 63.