abstract |
The invention discloses a transdermal drug delivery drug composition, which comprises sufentanil or pharmaceutically acceptable salt thereof, a high molecular dispersion carrier material, a hot melt protective agent and an optional fluxing agent. In addition, a preparation method and application of the pharmaceutical composition are also provided. The transdermal drug delivery composition can ensure that sufentanil is rapidly absorbed, achieves the purpose of treating postoperative pain, does not influence respiration, and avoids adverse psychological effects of intramuscular injection or intravenous injection acupuncture on patients. Meanwhile, the pharmaceutical composition can also be used for preventing and/or treating postherpetic neuralgia. |