| abstract |
The invention discloses an alfacalcidol soft capsule and a preparation method thereof, and specifically relates to the technical field of pharmaceutical preparations, comprising a soft capsule filling liquid and a soft capsule shell. The components are prepared from: 35-50 parts of alfacalcidol, 5-10 parts of polyethylene glycol, 50-80 parts of coconut oil base, 10-15 parts of digestive enzymes, the auxiliary materials include by weight: accelerator 10-20 parts, antioxidant 30-60 parts, the soft capsule shell is 60-70 parts by weight of gelatin, 20-28 parts of glycerin, 25-35 parts of beeswax and 30-45 parts of water. The present invention prepares the filling liquid by using the coconut oil base and digestive enzymes, has excellent waterproof and heat resistance, is easy to store, and does not need to add a curing agent and a thickening agent, and the auxiliary added digestive enzymes can help the user to decompose the coconut oil base, effectively The absorption effect of alfacalcidol is improved to meet the needs of patients. |