http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111419792-B

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filingDate 2020-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111419792-B
titleOfInvention A kind of compound Liuanca injection and preparation method thereof
abstract The invention provides a compound Liuanca injection, which is composed of the following raw and auxiliary materials in parts by weight and volume: 123-227 parts by weight of sodium salicylate, 35-65 parts by weight of antipyrine, and 18-32 parts by weight of caffeine. In parts by weight, 0.1-0.3 parts by weight of disodium edetate, 1-3 parts by weight of sodium bisulfite, 1,000 parts by volume of water, and a pH adjuster are added to make the injection pH 6.8-7.2. Aiming at the problems of easy hydrolysis and instability of the existing compound Liu'anca injection, the present invention adopts disodium edetate as a chelating agent, and sodium bisulfite as an antioxidant, so as to effectively ensure that the compound Liu'anca injection can be used in 24 months. The internal quality is more stable, and at the same time, the increase of inactive and uncontrollable impurities caused by the instability of excipients is avoided, the safety of the injection is improved, and it has practical application and promotion value.
priorityDate 2020-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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