http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111413422-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-062 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-74 |
filingDate | 2020-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111413422-B |
titleOfInvention | Choline-proline ionic liquid modified magnetic nanomaterials and its detection method for aprelate combined with HPLC |
abstract | The invention belongs to the field of drug analysis, and discloses a choline-proline ionic liquid modified magnetic nanometer material and a method for detecting aprelate combined with HPLC. Choline-proline ionic liquid [Ch][Pro] was modified to the surface of Fe 3 O 4 @SiO 2 by cross-linking agent 1,6-hexamethylene diisocyanate (HDI), and the material was used to extract love in actual samples. Plet, and combined with high performance liquid chromatography-ultraviolet detector to determine its content. The results show that: Fe 3 O 4 @SiO 2 @HDI@[Ch][Pro] nanoparticles can quickly adsorb aprelide, and the extraction rate of aprelide in actual samples can reach more than 96%. The limit is 2.0ng mL ‑1 , the linear range is 0.01‑20 μg mL ‑1 , and the enrichment factor is 13. The method was successfully applied to the determination of aprelide in tablets and serum samples. |
priorityDate | 2020-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.