| abstract |
The invention particularly relates to a medical hydrogel dressing, a preparation method and application thereof, wherein the medical hydrogel dressing comprises mesenchymal stem cells, modified fibronectin, glycidyl methacrylate xanthan gum and nano microcapsule hydrogel. The preparation method of the medical hydrogel comprises the following steps: the nano microcapsule for encapsulating the stem cell growth factor is prepared by an improved double-emulsion method, the nano microcapsule and glycidyl methacrylate xanthan gum are mixed and coated on a polypropylene mesh, modified fibronectin is added on the surface of hydrogel, and the hydrogel dressing with stable structure is formed by illumination. The hydrogel is made of natural materials, so that the hydrogel has extremely high biocompatibility and can be used as a scaffold for cell growth. The mesenchymal stem cells are carried, the slow release of stem cell growth factors is controlled through a nanotechnology, a proper microenvironment is provided for the growth of the stem cells, the stem cells are proliferated and differentiated by themselves and recruited by paracrine, the tissue healing is accelerated, the lesion repair is accelerated, and the clinical application prospect is good. |