http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111398473-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d20479506b38eb222093717b99a5d5ed |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-8679 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
| filingDate | 2020-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7e63fe06048babee78106362a0a22d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b51822e5199c15614a96fa58767de955 |
| publicationDate | 2020-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111398473-A |
| titleOfInvention | Method for separating and detecting degradation impurities in dutasteride preparation by HP L C method |
| abstract | The invention discloses a method for separating and detecting degraded impurities in a dutasteride preparation by an HP L C method, which comprises the following steps of a, selecting 100mg of dutasteride raw material medicine, adding a mobile phase, and quantitatively diluting to 100 mu g/ml ‑1 A control solution; step b: precisely measuring 1.0ml,2.0ml,4.0ml and 8.0ml of the dutasteride solution and the reference substance solution in the step a, respectively placing the dutasteride solution and the reference substance solution in 10ml volumetric flasks, dissolving and diluting the dutasteride solution and the reference substance solution to a scale by using a mobile phase, and then fully shaking the solution uniformly for later use; step c: respectively injecting 20 mu l of dutasteride solution and reference substance solution obtained in the step b, and performing chromatographyThe method for separating and detecting the degradation impurities in the dutasteride preparation by using the HP L C method in the application has the advantages of simple and convenient operation, sensitivity, high accuracy and specificity, can be widely applied to quality control of the dutasteride preparation, can fully separate the impurities, and does not influence the accuracy of the detection method recorded in the application. |
| priorityDate | 2020-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.