| abstract |
The invention discloses a compound, which is synthesized by taking phellodendron ketone as a raw material, and is a compound shown in a formula (1), or a stereoisomer, a geometric isomer, a tautomer, an oxynitride, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug of the compound shown in the formula (1); the compound (1) disclosed by the invention can better enhance the action of glucocorticoid, reduce the dosage of glucocorticoid and reduce the toxic and side effects of glucocorticoid, and can effectively enhance the glucocorticoid to inhibit the generation of NO, thereby playing a better role in enhancing the glucocorticoid. |