http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111393243-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-1815 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-2404 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B53-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B53-00 |
| filingDate | 2020-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111393243-B |
| titleOfInvention | A kind of synthetic method of phosphoric chiral nucleoside drug and the drug obtained by the method |
| abstract | The invention discloses a method for synthesizing phosphochiral nucleoside drugs, comprising the following steps: reacting a phosphonochloride compound and a nucleoside prodrug with a hydroxyl group under the catalysis of a chiral transition metal catalyst to obtain phosphochiral nucleosides drug. The method adopts a specific catalyst and controls the reaction conditions, thereby improving the yield and enantioselectivity of the phosphoric chiral nucleoside drugs, and the method is simple and easy, suitable for scaled-up production, and has great popularization value. |
| priorityDate | 2020-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 105.