http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111374952-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1611 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1652 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 |
filingDate | 2018-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111374952-B |
titleOfInvention | Acarbose pharmaceutical composition and preparation method thereof |
abstract | The present invention relates to acarbose pharmaceutical composition and its preparation method. The pharmaceutical composition comprises acarbose, a filler, a lubricant, and optionally a glidant, and is prepared by a one-step granulation process. The present invention uses water or low-concentration ethanol solution as the wetting agent, avoiding the danger of using high-concentration ethanol solution as the wetting agent; realizing two steps of granulation and drying into one step, saving the trouble of transferring materials; Silica is dispersed in the wetting agent and added to the material by spraying or using silicified microcrystalline cellulose to solve the problem of electrostatic aggregation and dissolution of large RSD caused by direct addition of silica, and to ensure more uniform quality. |
priorityDate | 2018-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 119.