http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111363013-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 |
filingDate | 2018-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111363013-B |
titleOfInvention | Construction method of multi-component nanoparticle cluster |
abstract | The invention provides a construction method of the multi-component nanoparticle cluster, which comprises the following steps: respectively providing N zinc finger proteins, N protein tags and M nanoparticles; crosslinking one kind of the nanoparticles with at least one kind of the protein tags, and crosslinking only one kind of the nanoparticles with one kind of the protein tags to obtain N kinds of nanoparticle/protein tag complexes; crosslinking one zinc finger protein with one ligand according to the unique pairing relation to obtain N zinc finger protein/ligand complexes; providing a nucleotide sequence, mixing and incubating the nucleotide sequence with the N types of nano-particle/protein tag complexes and the N types of zinc finger protein/ligand complexes to form a nucleotide sequence-zinc finger protein-protein tag-nano-particle connecting system, and collecting the obtained nano-particle cluster after separation, wherein bases in the nucleotide sequence are set according to the preset arrangement sequence of zinc finger proteins in the nano-particle cluster. |
priorityDate | 2018-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 144.