http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111362834-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C257-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C319-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C257-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C319-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
| filingDate | 2020-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111362834-B |
| titleOfInvention | Antibacterial amidine oligomer with drug resistance and preparation method and application thereof |
| abstract | The invention discloses an antibacterial amidine oligomer with drug resistance and a preparation method and application thereof, wherein the antibacterial species of the amidine oligomer comprise bacillus subtilis, escherichia coli, enterococcus faecalis, staphylococcus aureus, klebsiella pneumoniae, acinetobacter baumannii, pseudomonas aeruginosa and enterobacter cloacae. The structure disclosed by the invention has a dual antibacterial mechanism of destroying cell membranes and combining with chromosome DNA, has the characteristics of quick sterilization and drug resistance, and shows broad antibacterial spectrum. In addition, the structure utilizes the difference that the bacteria have no cell nucleus and the bacteria have the cell nucleus, specifically targets the DNA of the bacteria, obviously reduces the cytotoxicity and improves the therapeutic index of the bacteria. |
| priorityDate | 2020-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.