Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_598a905b1081c2f3e1a0bb3bd85f23c1 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5047 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6854 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-15 |
filingDate |
2018-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11a46a7c82219f804e7859c0f053988a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bafd1e14135fb2f8070784e8f828a2d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_412295f58552c3efd1e75113aff1d3f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c25fb84972c8cdd7a21406da0a5d3f8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_508316ad91cea0b361c57e35f8bb7418 |
publicationDate |
2020-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-111351921-A |
titleOfInvention |
Food sensitization animal model, construction method and application thereof |
abstract |
The invention provides a food allergen sensitized animal model, a construction method and application thereof. The invention carries out mouse immune reconstruction through healthy human peripheral blood cells, and carries out human immune reconstruction on an immune-deficient mouse by adopting an optimized food allergen extraction method, food allergenic protein quantity and optimized human immune cell quantity, thereby obtaining a food allergenic protein sensitized human immune reconstructed mouse model which has high success rate and can be successfully carried out by healthy human blood, and providing a simple and quick drug effect evaluation method for drug effect evaluation of allergic disease drugs. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113892461-A |
priorityDate |
2018-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |