http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111349128-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-07 |
| filingDate | 2018-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2023-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2023-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111349128-B |
| titleOfInvention | Flavonol derivatives and their preparation methods and applications |
| abstract | The invention discloses a flavonol derivative as well as its preparation method and application. Specifically, the present invention discloses a flavonol derivative shown in formula I, or a pharmaceutically acceptable salt thereof, or an enantiomer, diastereoisomer, tautomer, solvate thereof , polymorph or prodrug, wherein, R 1 and R 2 are independently selected from: -OH, -OC (=O) R a ; R a is substituted or unsubstituted C 2 -C 12 alkenyl; R 3 is selected from: hydrogen, C 1 -C 6 substituted or unsubstituted alkoxy; R 4 is selected from: hydrogen, cyclic monosaccharide sugar group; unless otherwise specified, the "substitution" refers to one or Multiple hydrogen atoms are substituted by substituents selected from the group consisting of -OH, C 1 -C 4 alkyl. The flavonol compound of the present invention has an excellent blood lipid-lowering effect, and can significantly reduce the levels of TG, CHO, and LDL-C in blood lipids. |
| priorityDate | 2018-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.