abstract |
The present invention relates to aminopyrimidine compounds with inhibitory effect on protein kinase activity, as well as their preparation and use. Specifically, the present invention discloses an aminopyrimidine compound represented by formula (I), or a pharmaceutically acceptable salt, stereoisomer, solvate or hydrate thereof, and a pharmaceutical composition containing the compound and its use Methods thereof, including methods of treating cell proliferative diseases and disorders such as cancer and immune diseases. |